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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4277 | Osilodrostat | LCI699 | Glucocorticoid Receptor , Others , Hydroxylase |
Osilodrostat (LCI699) (LCI699) is an effective inhibitor of human 11β-hydroxylase (IC50: 2.5 nM) and aldosterone synthase (IC50: 0.7 nM). | |||
T61373 | Baxdrostat | Others | |
Baxdrostat is an aldosterone synthase inhibitor. | |||
T1866 | AT-56 | Others , PGE Synthase | |
AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects. | |||
T62747 | Lorundrostat | ||
Lorundrostat is an aldosterone synthase inhibitor. | |||
T61372 | (S)-Baxdrostat | ||
(S)-Baxdrostat is an S-enantiomer of Baxdrostat, which functions as an inhibitor of aldosterone synthase [1]. | |||
T14664 | BI 689648 | Others | |
BI 689648 is a highly selective inhibitor of aldosterone synthase(CYP11B1 and CYP11B2 with IC50s of 310 and 2.1 nM, respectively). | |||
T73896 | Glucose-6-phosphate dehydrogenase | ||
Glucose-6-phosphate dehydrogenase, the crucial rate-limiting enzyme in the pentose phosphate pathway, plays a vital role in generating NADPH. This compound is indispensable for numerous critical cellular functions such a... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T39991 | 18-Oxocortisol | ||
18-Oxocortisol is a cortisol derivative generated by aldosterone synthase (CYP11B2). It acts as a naturally occurring mineralocorticoid agonist and serves as a biomarker in adrenal vein sampling. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01181 | CYP11B2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
CYP11B2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPJ-00240 | CAMK1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed.... |